Osteoarthritis (OA) is a complex multi-target disease with an unmet medical need for the development of therapies that slow and potentially revert disease progression. Intra-articular (IA) delivery has seen a surge in osteoarthritis research in recent years. As local administration of molecules. this represents a way to circumvent systemic drug delivery struggles. https://www.relicsbook.com/product-category/autographed-framed-historical-photos/