Abstract Valproic acid (VPA) exposure as an environmental factor that confers risk of autism spectrum disorder (ASD). its functional mechanisms in the human brain remain unclear since relevant studies are currently restricted to two-dimensional cell cultures and animal models. To identify mechanisms by which VPA contribute to ASD risk in human. here we used human forebrain organoids (... https://www.roneverhart.com/Dr-Squish-Squishy-Refill/