Background: Interleukin-31 has been linked with developing and maintaining pruritus in various dermatological and non-dermatological diseases. Objectives: To evaluate interleukin-31 serum levels in hemodialysis patients with and without uremic pruritus as a potential contributor. Methods: This cross-sectional study involved ninety adult chronic kidney disease patients on hemodialysis. https://www.chiggate.com/